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1. (WO2018204495) NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS METHODS AND SYSTEMS FOR LOADING RNA
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Pub. No.: WO/2018/204495 International Application No.: PCT/US2018/030648
Publication Date: 08.11.2018 International Filing Date: 02.05.2018
IPC:
C07K 14/705 (2006.01) ,C07K 14/775 (2006.01) ,C07F 9/09 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
775
Apolipopeptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9
Compounds containing elements of the 5th Group of the Periodic System
02
Phosphorus compounds
06
without P-C bonds
08
Esters of oxyacids of phosphorus
09
Esters of phosphoric acids
Applicants:
SYNTHETIC GENOMICS, INC. [US/US]; 11149 North Torrey Pines Road, Suite 100 La Jolla, CA 92037, US
Inventors:
KAMRUD, Kurt, I.; US
WANG, Nathaniel, S.; US
FELDERMAN, Martina; US
HUBBY, Bolyn; US
GOUVIS, Heather, D.; US
FISCHER, Nicholas, O.; US
COLEMAN, Matthew, A.; US
EVANS, Angela, Clare; US
HE, Wei; US
RASLEY, Amy; US
BLANCHETTE, Craig, D.; US
Agent:
HAILE, Lisa, A.; US
JACKSON, Blake; US
LIMBACH, Alan, A.; US
HIERHOLZER, Matthew, J.; US
HWANG, Palela, E.; US
Priority Data:
62/500,43302.05.2017US
Title (EN) NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS METHODS AND SYSTEMS FOR LOADING RNA
(FR) PARTICULES DE NANOLIPOPROTÉINE ET COMPOSITIONS, PROCÉDÉS ET SYSTÈMES ASSOCIÉS POUR LE CHARGEMENT D'ARN
Abstract:
(EN) Nanolipoprotein particles comprising at least a scaffold protein component and a membrane lipid component and related complexes, compositions, methods and systems are described, in which the membrane lipid component comprises at least one or more membrane forming lipids and one or more cationic lipids.
(FR) La présente invention concerne des particules de nanolipoprotéine comprenant au moins un composant de type protéine d'échafaudage et un composant de type lipide membranaire ainsi que des complexes, compositions, procédés et systèmes associés, le composant de type lipide membranaire comprenant au moins un ou plusieurs lipides formant une membrane et un ou plusieurs lipides cationiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)