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1. (WO2018204394) COMPOSITIONS AND METHODS FOR THE TREATMENT OF ZIKA VIRAL DISEASES

Pub. No.:    WO/2018/204394    International Application No.:    PCT/US2018/030500
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Wed May 02 01:59:59 CEST 2018
IPC: A61K 31/4184
A61K 31/4412
A61K 31/713
Applicants: THE PROIMMUNE COMPANY L.L.C.
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION
Inventors: CRUM, Albert
HILLIARD, Julia
Title: COMPOSITIONS AND METHODS FOR THE TREATMENT OF ZIKA VIRAL DISEASES
Abstract:
Embodiments of the present invention relate generally the use of compositions comprising a glutathione precursor and a selenium source, e.g., compositions which elevate intracellular glutathione, in the prevention and treatment of Zika viral diseases, e.g., Zika fever. Related embodiments are directed to use of such compositions, e.g., compositions comprising a glutathione precursor and a selenium source, in reducing the infectivity of Zika viruses or Zika viral particles.