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1. (WO2018204286) AN ANTI-CANCER STEMNESS DRUG

Pub. No.:    WO/2018/204286    International Application No.:    PCT/US2018/030300
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Tue May 01 01:59:59 CEST 2018
IPC: A61K 31/4439
A61P 25/00
C07D 401/04
Applicants: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
DCB-USA LLC
Inventors: WU, Cheng-Wen
LIN, Erh-Hsuan
HUANG, Chi-Ying
CHANG, Jia-Ming
CHUANG, Shih-Hsien
HSU, Hui-Jan
CHEN, Wei-Wei
Title: AN ANTI-CANCER STEMNESS DRUG
Abstract:
A compound for inhibiting BMI-l/MCL-1 having a structure of Formula (I), wherein the various groups are as described. A pharmaceutical composition for treating cancer includes an effective amount of a compound of Formula (I).