Search International and National Patent Collections

1. (WO2018203834) METHODS FOR CULTURING HUMAN KERATINOCYTES

Pub. No.:    WO/2018/203834    International Application No.:    PCT/SG2018/050220
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Sat May 05 01:59:59 CEST 2018
IPC: C12N 5/071
A61K 35/36
G01N 33/50
Applicants: NATIONAL UNIVERSITY OF SINGAPORE
SINGAPORE HEALTH SERVICES PTE LTD
Inventors: TRYGGVASON, Karl
TJIN, Monica Suryana
CHUA, Alvin Wen Choong
Title: METHODS FOR CULTURING HUMAN KERATINOCYTES
Abstract:
The present disclosure relates to methods for culturing human epidermal keratinocytes. When keratinocytes are cultured on plates coated with a laminin containing an alpha-4 chain or an alpha-5 chain, in a xeno-free, chemically defined cell culture medium, they expand efficiently in vitro. Useful cell culture kits for culturing keratinocytes are also described herein, as are methods of using such cells for treatment of burns or chronic wounds.