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1. (WO2018203515) METHOD AND DEVICE FOR EVALUATING LACRIMAL FLUID LAYER DYNAMICS

Pub. No.:    WO/2018/203515    International Application No.:    PCT/JP2018/017115
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Sat Apr 28 01:59:59 CEST 2018
IPC: A61B 3/10
Applicants: KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION
京都府公立大学法人
KOWA COMPANY, LTD.
興和株式会社
Inventors: YOKOI Norihiko
横井 則彦
YABUSAKI Katsumi
薮崎 克己
Title: METHOD AND DEVICE FOR EVALUATING LACRIMAL FLUID LAYER DYNAMICS
Abstract:
Provided are a method and device for evaluating the dynamics of a lacrimal fluid layer in order to objectively and accurately evaluate breakdown of the lacrimal fluid layer, which is a core mechanism of dry eye. The present invention includes a step for acquiring color information of each pixel in a predetermined region of a lacrimal fluid layer interference fringe image, which is a moving image or a plurality of static images, a step for calculating a numerical value indicating the diversity of color from the acquired color information, a step for calculating the average value of the color information, and a step for calculating a fluctuation coefficient on the basis of the calculated numerical value indicating the color diversity and the average value of the color information, the fluctuation coefficient being used as an index for evaluating the dynamics of the lacrimal fluid layer.