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1. (WO2018202931) METHOD FOR DIAGNOSING UNSTABLE ATHEROSCLEROSIS PLAQUES

Pub. No.:    WO/2018/202931    International Application No.:    PCT/ES2018/070338
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Sat May 05 01:59:59 CEST 2018
IPC: C12Q 1/6883
Applicants: UNIVERSIDAD DEL PAÍS VASCO/EUSKAL HERRIKO UNIBERTSITATEA
ADMINISTRACIÓN GENERAL DE LA COMUNIDAD AUTÓNOMA DE EUSKADI
Inventors: ALLOZA MORAL, Iraide
VANDENBROECK, Koen
FREIJO GUERRERO, María del Mar
VEGA MANRIQUE, Reyes
Title: METHOD FOR DIAGNOSING UNSTABLE ATHEROSCLEROSIS PLAQUES
Abstract:
The present invention relates to a method for diagnosing unstable atherosclerosis plaques, using a method to determine the probability of a person suffering from a cerebrovascular disease and a method to select a patient that could be treated with a therapy to eliminate or stabilise the carotid atherosclosis plaque on the basis of the determination of the expression level of at least one gene selected from the group of genes shown in table 1. The invention also relates to a kit comprising suitable reagents for determining the expression levels of at least one gene selected from the group of genes shown in table 1 and, optionally, reagents for determining the expression levels of one or more caretaker genes, and to the uses of said kit.