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1. (WO2018202666) CPG-SITE METHYLATION MARKERS IN COLORECTAL CANCER

Pub. No.:    WO/2018/202666    International Application No.:    PCT/EP2018/061118
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Thu May 03 01:59:59 CEST 2018
IPC: C12Q 1/68
Applicants: DEUTSCHES KREBSFORSCHUNGSZENTRUM
Inventors: JIA, Min
HOFFMEISTER, Michael
Title: CPG-SITE METHYLATION MARKERS IN COLORECTAL CANCER
Abstract:
The present invention relates to a method for determining a survival probability of a subject suffering from colorectal cancer comprising a) detecting the methylation status of at least two CpG sites selected from the CpG sites of Table 1 in a sample of said subject and, b) based on the methylation status detected in step a), determining the survival probability of said subject. The present invention further relates to a use of the methylation status of genomic DNA or means for the determination thereof in a sample of a subject suffering from colorectal cancer for determining a survival probability of said subject, preferably for predicting the mortality risk of said subject, and to a data collection, a kit, and a device related thereto.