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1. (WO2018202649) BISPECIFIC ANTIBODY AGAINST OX40 AND CTLA-4

Pub. No.:    WO/2018/202649    International Application No.:    PCT/EP2018/061084
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Wed May 02 01:59:59 CEST 2018
IPC: C07K 16/28
A61P 35/00
A61K 39/00
Applicants: ALLIGATOR BIOSCIENCE AB
Inventors: ELLMARK, Peter
FUREBRING, Christina
NORLÉN, Per
VEITONMÄKI, Niina
Title: BISPECIFIC ANTIBODY AGAINST OX40 AND CTLA-4
Abstract:
The present invention provides bispecific polypeptides, such as bispecific antibodies, comprising a first binding domain capable of specifically binding to OX40, and a second binding domain capable of specifically binding to CTLA-4. The invention further provides compositions of said bispecific polypeptides, as well as methods and uses of the same.