Search International and National Patent Collections

1. (WO2018202155) BICYCLIC NUCLEOCAPSID INHIBITOR AND USE OF SAME AS DRUG IN TREATMENT OF HEPATITIS B

Pub. No.:    WO/2018/202155    International Application No.:    PCT/CN2018/085695
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Sat May 05 01:59:59 CEST 2018
IPC: C07D 487/04
Applicants: SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD.
上海长森药业有限公司
Inventors: WANG, Zhe
王喆
FAN, Guoqin
范国钦
LU, Cenbin
卢涔宾
YANG, Sai
杨赛
WANG, Xiaoguang
王晓光
Title: BICYCLIC NUCLEOCAPSID INHIBITOR AND USE OF SAME AS DRUG IN TREATMENT OF HEPATITIS B
Abstract:
The present invention relates to a bicyclic nucleocapsid inhibitor and the use of the same as a drug in the treatment of hepatitis B. In particular, disclosed is a compound having the structure as shown in chemical formula A, or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt, a hydrate or a solvate thereof that can be used as an HBV inhibitor, wherein the definition of each group is as described in detail in the description. The present invention also relates to a pharmaceutical composition comprising the compound and the use of the same in the treatment of hepatitis B.