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1. (WO2018202107) PHARMACEUTICAL COMPOSITION FOR TREATING HYPERLIPIDEMIA AND ATHEROSCLEROSIS

Pub. No.:    WO/2018/202107    International Application No.:    PCT/CN2018/085524
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Sat May 05 01:59:59 CEST 2018
IPC: A61K 31/715
A61K 31/7028
A61K 31/435
A61K 31/365
A61K 31/352
A61K 9/08
A61K 9/20
A61K 9/48
A61P 9/10
A61P 3/06
Applicants: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
中国科学院上海药物研究所
Inventors: HUANG, Chenggang
黄成钢
LI, Zhixiong
李志雄
GAO, Yu
高羽
TIAN, Xiaoting
田小亭
SUN, Zhaolin
孙兆林
CHEN, Mingcang
陈明苍
HU, Pei
胡培
LIU, Huan
刘欢
XU, Zhou
徐洲
Title: PHARMACEUTICAL COMPOSITION FOR TREATING HYPERLIPIDEMIA AND ATHEROSCLEROSIS
Abstract:
A pharmaceutical composition for treating hyperlipemia and atherosclerosis, comprising: an active component and a pharmaceutically acceptable carrier. The active component is a combination of two or more of puerarin, daidzin, genistin, daidzein, calycosin-7-glucoside, astragalus saponin II, astragaloside, formononetin, mulberroside A, morusin, scopoletin, sanggenon C, 1-deoxynojirimycin, puerarin polysaccharide, astragalus polysaccharide, and white mulberry root-bark polysaccharide. The pharmaceutical composition can reduce the area of fatty plaque in the aorta of atherosclerotic model apoE-/- transgenic mice and reduce the blood lipids of hyperlipidemic mice, and can treat hyperlipemia and atherosclerosis.