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1. (WO2018201981) IMMUNOMAGNETIC COMPOSITION, PREPARATION METHOD AND USE THEREOF, AND KIT FOR TREATING CANCER
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Pub. No.: WO/2018/201981 International Application No.: PCT/CN2018/084769
Publication Date: 08.11.2018 International Filing Date: 27.04.2018
IPC:
A61K 31/737 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
715
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
737
Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
中国医药大学 CHINA MEDICAL UNIVERSITY [CN/CN]; 中国台湾省台中市 北区学士路91号 No.91, Xueshi Rd., North Dist. Taichung City 404, Taiwan, CN
Inventors:
徐伟成 SHYU, Woei-Cherng; CN
陈三元 CHEN, San-Yuan; CN
江智圣 CHIANG, Chih-Sheng; CN
谢佳宏 HSIEH, Chia-Hung; CN
林佑融 LIN, Yu-Jung; CN
蔡长海 TSAI, Chang-hai; CN
Agent:
北京中誉威圣知识产权代理有限公司 GENUINEWAYS INC.; 中国北京市 东城区东四块玉南街32号鸿运商务楼三层 F3 Hong Yun Business Building No.32, Dongsikuaiyu South Street, Dongcheng District Beijing 100061, CN
Priority Data:
201810051881.816.01.2018CN
62/492,52501.05.2017US
Title (EN) IMMUNOMAGNETIC COMPOSITION, PREPARATION METHOD AND USE THEREOF, AND KIT FOR TREATING CANCER
(FR) COMPOSITION IMMUNOMAGNÉTIQUE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION, ET KIT DE TRAITEMENT DU CANCER
(ZH) 免疫磁性组成物及其制备方法、用途和治疗癌症的试剂盒
Abstract:
(EN) An immunomagnetic composition, a preparation method and a use thereof, and a kit for treating a cancer. The immunomagnetic composition comprises a core layer, a shell layer, and an outer layer. The shell layer is composed of a composite and encapsulates the core layer. The composite is formed by the combination of fucoidan, oxidized dextran, and a plurality of superparamagnetic iron oxide nanoparticles by hydrophobic interaction. The outer layer comprises at least one antibody.
(FR) L'invention concerne une composition immunomagnétique, un procédé de préparation et une utilisation de celle-ci, et un kit pour traiter un cancer. La composition immunomagnétique comprend une couche centrale, une couche d'enveloppe et une couche externe. La couche d'enveloppe est composée d'un composite et encapsule la couche centrale. Le composite est formé par la combinaison de fucoïdane, de dextrane oxydé et d'une pluralité de nanoparticules d'oxyde de fer superparamagnétique par interaction hydrophobe. La couche externe comprend au moins un anticorps.
(ZH) 一种免疫磁性组成物及其制备方法、用途和治疗癌症的试剂盒,免疫磁性组成物包含核心层、壳层以及外层。壳层由复合物构成,壳层包覆核心层。复合物由褐藻多糖、氧化右旋糖酐及多个超顺磁性氧化铁纳米粒子经疏水性作用力结合而形成。外层包含至少一种抗体。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)