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1. (WO2018200981) RAF-DEGRADING CONJUGATE COMPOUNDS
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Pub. No.: WO/2018/200981 International Application No.: PCT/US2018/029837
Publication Date: 01.11.2018 International Filing Date: 27.04.2018
IPC:
A61K 48/00 (2006.01) ,C07H 21/02 (2006.01) ,C07H 21/04 (2006.01)
[IPC code unknown for A61K 48][IPC code unknown for C07H 21/02][IPC code unknown for C07H 21/04]
Applicants:
QUARTZ THERAPEUTICS, INC. [US/US]; 165 University Avenue Suite 5 Palo Alto, California 94301, US
Inventors:
ZAMBONI, Robert; US
HENNING, Ryan; US
JI, Xian Alan; US
SMITH, Tyler; US
HELLER, Bradley; US
REDDY, Thumkunta Jagadeeswar; US
ROCHELEAU, Sylvain; US
BEAULIEU, Marc Andre; US
Agent:
DOLAN, Gregory F.; US
KEZER, William B.; US
ADAMS, Lisa; US
AMENDT, Kevin C.; US
AZRIN, Linda B.; US
BAUER, John A.; US
BEATTIE, Ingrid A.; US
BOLCOME III, Robert E.; US
CARROLL, Lawrence J.; US
CHANG, Jinhee; US
CLEARY, James P.; US
COLLINS, Daniel W.; US
CONLIN, David G.; US
CONSTANTINE, Derek E.; US
CORLESS, Peter F.; US
CRONIN, Thomas C.; US
CUOMO, Peter J.; US
DAHLIN, Inna; US
FORREST, John B.; US
GEARY, William C.; US
GERVASE, Richard G.; US
GITTES, Marvin S.; US
GRIEFF, Edward D.; US
GRYGIEL, Sean J.; US
HERNANDEZ, Fred C.; US
HETZER, Claudia; US
DANG, David V.; US
HUDSON, Benjamin F.; US
JEFFERS, Christopher E.; US
JENKINS, Kenneth E.; US
JENSEN, Katherine C.; US
JENSEN, Steven M.; US
KIM, Kongsik; US
LATTA, Robert T.S.; US
LEE, Joonhee; US
LIBERTO, Muriel; US
MACEK, Monique; US
MANSO, Peter J.; US
MATTONI, Michael A.; US
MATVENKO, Borris; US
MITRA, Linyu L.; US
MOUTON, Nicholas P.; US
NOMURA, Anson M.; US
PARSONS, Elizabeth; US
PINO, Mark J.; US
SAVE, Carolina E.; US
SCHELLER, Brad M.; US
SCHILLER, Natalie K.; US
SHIEH-NEWTON, Terri; US
SHOW, Matthew D.; US
SINGH, Gurneet; US
SCALE, Andrew D.; US
SLONIM, Timur; US
SNELL, Peter F.; US
SPERRY, Christina; US
SUAREZ, Pedro F.; US
TERRANOVA, Zachary L.; US
TRIMBLE, Alexander R.; US
VAN LOY, Michael D.; US
WEINLICK, Erin P.; US
WESTERN, Jonathon P.; US
WITHERELL, Colleen H.; US
ZACHARIADES, Nicholas A.; US
ZHANG, Lily; US
Priority Data:
62/491,92528.04.2017US
62/581,46403.11.2017US
Title (EN) RAF-DEGRADING CONJUGATE COMPOUNDS
(FR) COMPOSÉS CONJUGUÉS DE DÉGRADATION DE RAF
Abstract:
(EN) The present disclosure provides, inter alia, RAF-Degrading Conjugate Compounds that are useful in the treatment of cancer and other RAF related diseases. Also provided are, pharmaceutical compositions, methods of treatment, and kits comprising a RAF- Degrading Conjugate Compound.
(FR) La présente invention concerne, entre autres, des composés conjugués de dégradation de RAF qui sont utiles dans le traitement du cancer et d'autres maladies associées à RAF. L'invention concerne également des compositions pharmaceutiques, des méthodes de traitement et des trousses comprenant un composé conjugué de dégradation de RAF.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)