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1. (WO2018200975) HEPATITIS C VIRUS GENE SEQUENCES AND METHODS OF USE THEREFOR

Pub. No.:    WO/2018/200975    International Application No.:    PCT/US2018/029826
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Sat Apr 28 01:59:59 CEST 2018
IPC: A61K 39/12
A61K 39/29
A61K 39/39
Applicants: VANDERBILT UNIVERSITY
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
THE JOHNS HOPKINS UNIVERSITY
Inventors: CROWE, James, E.
FLYAK, Andrew
BAILEY, Justin
RAY, Stuart
SHAW, George
Title: HEPATITIS C VIRUS GENE SEQUENCES AND METHODS OF USE THEREFOR
Abstract:
The present disclosure relates to compositions and methods for inducing an adaptive immune response against Hepatitis C virus (HCV) in a subject. In some embodiments, the present disclosure provides a composition comprising a nucleic acid molecule encoding a HCV antigen, an HCV antigen, an adjuvant, or a combination thereof. For example, in some embodiments, the composition comprises a vaccine comprising a nucleic acid molecule encoding a HCV antigen, an HCV antigen, an adjuvant, or a combination thereof.