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1. (WO2018200951) MULTI-TARGETED MULTI-VALENT LIGAND-DRUG PARTICLES FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS

Pub. No.:    WO/2018/200951    International Application No.:    PCT/US2018/029790
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Sat Apr 28 01:59:59 CEST 2018
IPC: A61K 9/107
A61K 47/48
A61K 47/69
Applicants: TRAN, David T.
Inventors: TRAN, David T.
Title: MULTI-TARGETED MULTI-VALENT LIGAND-DRUG PARTICLES FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS
Abstract:
This disclosure relates to novel ligand-drug particles comprising at least one ligand specific for one or more cell surface receptor molecules for targeting the conjugate particles to a target cell. This disclosure also relates to pharmaceutical compositions comprising the particles herein and systems and methods for determining the ligand valency of the particles.