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1. (WO2018200894) METHODS AND MICROORGANISMS FOR THE FERMENTATION OF METHANE TO MULTI-CARBON COMPOUNDS

Pub. No.:    WO/2018/200894    International Application No.:    PCT/US2018/029688
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Sat Apr 28 01:59:59 CEST 2018
IPC: C12P 7/16
C12N 9/10
Applicants: INTREXON CORPORATION
Inventors: ORTH, Jeffrey David
CLARK, Louis A.
CHAO, Lily Yuin
TRINH, Na My
FARWELL, Christopher Cheney
ZHAO, Xinhua
SCHMALISCH, Matthias Helmut
WAWRZYN, Grayson Thomas
LI, Xuezhi
HELD, Mark Anton
DIETZEL, Kevin Lee
KEALEY, James
Title: METHODS AND MICROORGANISMS FOR THE FERMENTATION OF METHANE TO MULTI-CARBON COMPOUNDS
Abstract:
Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as isobutanol are disclosed. For example, genetically modified methanotrophs that are capable of generating isobutanol at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed.