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1. (WO2018200775) METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA

Pub. No.:    WO/2018/200775    International Application No.:    PCT/US2018/029518
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Fri Apr 27 01:59:59 CEST 2018
IPC: A61K 31/137
A61K 31/42
A61K 31/506
A61K 31/551
A61K 31/7008
A61K 45/06
Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
Inventors: WELLMAN, D. Andrew
TARANTO-MONTEMURRO, Luigi
Title: METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA
Abstract:
Methods and compositions for the treatment of conditions associated with pharyngeal airway muscle collapse while the subject is in a non-fully conscious state, e.g., sleep apnea and snoring, comprising administration of a norepinephrine reuptake inhibitor (NRI) and a muscarinic receptor antagonist.