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1. (WO2018200638) MATERIALS AND METHODS FOR PROTECTING AGAINST NEUROMAS

Pub. No.:    WO/2018/200638    International Application No.:    PCT/US2018/029305
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Thu Apr 26 01:59:59 CEST 2018
IPC: A61B 90/00
A61L 31/04
A61L 31/00
A61N 1/05
Applicants: AXOGEN CORPORATION
Inventors: DEISTER, Curt
SIMON, Crystal
FALERIS, Jennifer
Title: MATERIALS AND METHODS FOR PROTECTING AGAINST NEUROMAS
Abstract:
The subject invention provides devices and methods for alleviating discomfort associated with neuroma formation. The devices and methods of the invention effectively use the body's natural response of reconstructing implanted biomaterials to minimize the size of, isolate, and protect a neuroma. In preferred embodiments, the subject device is a cylindrical cap, wherein the internal chamber of the cylindrical cap physically partitions the nerve to enable an arrangement of nerve fibers (as opposed to haphazardly arranged nerve fibers often produced in neuromas). Tabs arranged on the outside of the cap can be used to manipulate the cap into place on a nerve. The open end can also be configured with flaps that can be used to widen the open end for easier insertion of the nerve into the cap. In addition, the cap's material remodels into a tissue cushion after implantation, which protects the neuroma from being stimulated and inducing pain.