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1. (WO2018200586) CONSTRUCTS SPECIFICALLY RECOGNIZING GLYPICAN 3 AND USES THEREOF

Pub. No.:    WO/2018/200586    International Application No.:    PCT/US2018/029221
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Wed Apr 25 01:59:59 CEST 2018
IPC: C07K 16/30
C07K 16/46
C07K 19/00
G01N 33/574
A61K 39/395
A61P 35/00
Applicants: EUREKA THERAPEUTICS, INC.
Inventors: ZHANG, Pengbo
XU, Yiyang
MORALES, Javier
NAKANO, Yoko
LIU, Hong
XIANG, Jingyi
ACKER, Timothy
Title: CONSTRUCTS SPECIFICALLY RECOGNIZING GLYPICAN 3 AND USES THEREOF
Abstract:
The present application provides constructs comprising an antibody moiety specifically recognizing Glypican 3 (GPC3), such as a cell surface-bound GPC3. Also provided are methods of making and using these constructs.