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|1. (WO2018200542) GENE THERAPY FOR OCULAR DISORDERS|
|Applicants:||THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
|Title:||GENE THERAPY FOR OCULAR DISORDERS|
Compositions and methods are provided for treating ocular neuropathy in a subject. In one aspect, a recombinant adeno-associated viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding NRF2. In another aspect, a recombinant adeno- associated viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding SIRT1. In desired embodiments, the subject is human, cat, dog, sheep, or non-human primate.