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1. (WO2018200061) AUTOMATED CONTROL OF MICROFLUIDIC DEVICES BASED ON MACHINE LEARNING

Pub. No.:    WO/2018/200061    International Application No.:    PCT/US2018/017699
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Sat Feb 10 00:59:59 CET 2018
IPC: G05D 7/06
B01L 3/00
Applicants: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
Inventors: GIERA, Brian
DUOSS, Eric, B.
NGUYEN, Du
TALATHI, Sachin, Subhash
SMITH, William
WILSON, Aaron, C.
YE, Congwang
Title: AUTOMATED CONTROL OF MICROFLUIDIC DEVICES BASED ON MACHINE LEARNING
Abstract:
A system is provided to automatically monitor and control the operation of a microfluidic device using machine learning technology. The system receives images of a channel of a microfluidic device collected by a camera during operation of the microfluidic device. Upon receiving an image, the system applies a classifier to the image to classify the operation of the microfluidic device as normal, in which no adjustment to the operation is needed, or as abnormal, in which an adjustment to the operation is needed. When an image is classified as normal, the system may make no adjustment to the microfluidic device. If, however, an image is classified as abnormal, the system may output an indication that the operation is abnormal, output an indication of a needed adjustment, or control the microfluidic device to make the needed adjustment.