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1. (WO2018199636) A COMBINATION FORMULATION COMPRISING HMG-COA REDUCTASE INHIBITOR AND CALCIUM CHANNEL BLOCKER
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Pub. No.: WO/2018/199636 International Application No.: PCT/KR2018/004815
Publication Date: 01.11.2018 International Filing Date: 25.04.2018
IPC:
A61K 9/20 (2006.01) ,A61K 9/28 (2006.01) ,A61K 31/4422 (2006.01) ,A61K 31/505 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
28
Dragees; Coated pills or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4422
1,4-Dihydropyridines, e.g. nifedipine, nicardipine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Applicants:
ALVOGEN KOREA CO.,LTD. [KR/KR]; 13 Fl., 10, Gukjegeumyung-ro, Yeongdeungpo-gu, Seoul 07326, KR
Inventors:
LEE, Si Beum; KR
HA, Song Yi; KR
HONG, Hye Suk; KR
LEE, Yoon Jung; KR
Agent:
SON, Min; KR
Priority Data:
10-2017-005387726.04.2017KR
Title (EN) A COMBINATION FORMULATION COMPRISING HMG-COA REDUCTASE INHIBITOR AND CALCIUM CHANNEL BLOCKER
(FR) FORMULATION COMBINÉE COMPRENANT UN INHIBITEUR DE LA HMG-COA RÉDUCTASE ET UN BLOQUEUR DES CANAUX CALCIQUES
Abstract:
(EN) The present invention relates to an oral combination formulation comprising a first composition comprising amlodipine or a pharmaceutically acceptable salt thereof, a disintegrant, and a sugar alcohol; and a second composition comprising rosuvastatin or a pharmaceutically acceptable salt thereof, and a stabilizer, and a preparation method thereof.
(FR) La présente invention concerne une formulation combinée orale comprenant une première composition comprenant de l'amlodipine ou un sel pharmaceutiquement acceptable de celle-ci, un délitant et un alcool de sucre ; et une seconde composition comprenant de la rosuvastatine ou un sel pharmaceutiquement acceptable de celle-ci et un stabilisant, ainsi que son procédé de préparation.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)