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|1. (WO2018199595) 4-1BBL MUTEIN AND FUSION PROTEIN COMPRISING SAME|
CHUNG, Eunju Esther
SHIN, Eun Ju
LIM, Hye Seong
LEE, Hae Jun
|Title:||4-1BBL MUTEIN AND FUSION PROTEIN COMPRISING SAME|
The present invention relates to a novel 4-1BBL mutein and a fusion protein comprising the same. The 4-1BBL mutein of the present invention may form a structurally stable trimer. Therefore, the trimer of the 4-1BBL mutein can effectively bind to 4-1BB in an individual. In addition, when various active proteins are bound to the trimer of the 4-1BBL mutein, the trimer can be used as an anticancer composition and a composition for preventing or treating infectious diseases.