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1. (WO2018199282) ORALLY ADMINISTRABLE ENZALUTAMIDE-CONTAINING PHARMACEUTICAL COMPOSITION

Pub. No.:    WO/2018/199282    International Application No.:    PCT/JP2018/017159
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Sat Apr 28 01:59:59 CEST 2018
IPC: A61K 31/4166
A61K 9/20
A61K 47/02
A61K 47/32
A61P 13/08
A61P 35/00
Applicants: ASTELLAS PHARMA INC.
アステラス製薬株式会社
Inventors: UMEMOTO Yoshiaki
梅本 佳昭
YOSHIDA Takatsune
吉田 貴恒
NAMIKI Sachie
並木 ▲祥▼恵
TAKAGI Akira
高木 彰
KOJIMA Ryo
小嶋 竜
SAKAI Toshiro
坂井 敏郎
OBA Shinsuke
大場 慎介
AOKI Hajime
青木 肇
Title: ORALLY ADMINISTRABLE ENZALUTAMIDE-CONTAINING PHARMACEUTICAL COMPOSITION
Abstract:
Provided is an orally administrable pharmaceutical composition in which the dissolution and/or elution properties of enzalutamide are improved and supersaturation is maintained. Also provided is an orally administrable pharmaceutical composition in which the oral absorbability of enzalutamide is improved. The orally administrable pharmaceutical composition contains enzalutamide and polyvinyl alcohol.