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|1. (WO2018199137) METHOD FOR DETECTING MINOR BCR-ABL1 GENE|
|Applicants:||OTSUKA PHARMACEUTICAL CO., LTD.
|Title:||METHOD FOR DETECTING MINOR BCR-ABL1 GENE|
The present invention provides a method including: (1) a step for performing PCR using a forward primer having a portion of the base sequence of exon 1 of the BCR gene and a reverse primer having a base sequence complementary to a portion of exons 2 through 11 of the ABL1 gene, with a nucleic acid sample obtained from a subject as a template, in the presence of a modified nucleic acid having the base sequence of a portion of exons 2 through 14 of the BCR gene or a base sequence complementary thereto; and (2) a step for determining that the subject has the minor BCR-ABL1 gene in the case that a nucleic acid is amplified by PCR.