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1. (WO2018199019) STENT
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Pub. No.: WO/2018/199019 International Application No.: PCT/JP2018/016449
Publication Date: 01.11.2018 International Filing Date: 23.04.2018
IPC:
A61F 2/848 (2013.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
82
Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
848
having means for fixation to the vessel wall, e.g. barbs
Applicants:
株式会社パイオラックスメディカルデバイス PIOLAX MEDICAL DEVICES, INC. [JP/JP]; 神奈川県横浜市保土ヶ谷区岩井町51番地 51, Iwai-cho, Hodogaya-ku, Yokohama-shi, Kanagawa 2400023, JP
国立研究開発法人国立がん研究センター NATIONAL CANCER CENTER JAPAN [JP/JP]; 東京都中央区築地5丁目1番1号 5-1-1 Tsukiji, Chuo-ku, Tokyo 1040045, JP
Inventors:
白川 京典 SHIRAKAWA Kyosuke; JP
吉川 恭央 YOSHIKAWA Yasuo; JP
高田 寛治 TAKADA Kanji; JP
矢野 友規 YANO Tomonori; JP
Agent:
松井 茂 MATSUI Shigeru; JP
Priority Data:
2017-09070328.04.2017JP
Title (EN) STENT
(FR) STENT
(JA) ステント
Abstract:
(EN) Provided is a stent which is capable of effectively supplying a medicinal substance such as an anticancer drug to tissue in which the stent is disposed, and in which a plurality of protrusions can be disposed stably on the outside of a stent main body. This stent 10 indwells inside a body and comprises: a stent main body 11 which is tubular and is provided in the circumferential direction thereof with a plurality of openings 13; a covering member 20 which is disposed outside the stent main body 11 and occludes at least some of the plurality of openings 13 in the stent main body 11; and a plurality of protrusions 30 which are provided projecting from a front side of the covering member 20 in such a way as to be disposed on the outside of the stent main body 11, and which are capable of latching onto a lesioned portion inside the body. At least some of the plurality of protrusions 30 form biodegradable portions comprising a biodegradable polymer, and a medicinal substance is contained in the biodegradable portions.
(FR) L'invention concerne un stent qui est capable d'apporter efficacement une substance médicamenteuse, telle qu'un médicament anticancéreux, jusqu'à un tissu dans lequel le stent est disposé, et dans lequel une pluralité de protubérances peuvent être disposées de façon stable à l'extérieur du corps principal du stent. Ce stent (10) est disposé à l'intérieur d'un organisme et comprend : un corps principal de stent (11) qui est tubulaire et qui comporte dans sa direction circonférentielle une pluralité d'ouvertures (13) ; un élément de recouvrement (20) qui est disposé à l'extérieur du corps principal du stent (11) et qui ferme au moins une partie de la pluralité d'ouvertures (13) situées dans le corps principal du stent (11) ; et une pluralité de protubérances (30) qui sont disposées en saillie à partir de la face avant de l'élément de recouvrement (20) de façon à être disposées à l'extérieur du corps principal du stent (11), et qui sont capables de s'attacher à une partie lésée à l'intérieur de l'organisme. Au moins certaines de la pluralité de protubérances (30) forment des parties biodégradables comprenant un polymère biodégradable, une substance médicamenteuse étant présente dans les parties biodégradables.
(JA) ステントが配置される組織に対して抗癌剤等の薬物を効果的に供給できると共に、ステント本体の外側に、複数の突起を安定して配置することができる、ステントを提供する。このステント10は、体内に留置されるものであって、筒状をなし、その周方向に複数の開口13を設けたステント本体11と、該ステント本体11の外側に配置され、ステント本体11の、複数の開口13の少なくとも一部を塞ぐ被覆部材20と、ステント本体11の外側に配置されるように、被覆部材20の表側から突設し、体内の病変部に係止可能とされた、複数の突起30とを有しており、複数の突起30の少なくとも一部は、生分解性ポリマーからなる生分解部をなしており、該生分解部に薬物が含有されている。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)