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1. (WO2018198084) CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES

Pub. No.:    WO/2018/198084    International Application No.:    PCT/IB2018/052936
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Sat Apr 28 01:59:59 CEST 2018
IPC: C07H 21/00
A61K 31/7084
A61P 31/00
A61P 35/00
Applicants: LUPIN LIMITED
Inventors: SINHA, Neelima
KARCHE, Navnath, Popat
KURHADE, Sanjay, Pralhad
JADHAV, Ganesh, Rajaram
HAJARE, Anil, Kashiram
GUPTA, Nishant, Ramniwasji
THUBE, Baban, Rupaji
SHAIKH, Javed, Shafi
PALLE, Venkata, P.
KAMBOJ, Rajender, Kumar
Title: CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES
Abstract:
The present invention relates to cyclic di-nucleotide compounds containing tricyclic heterocycles as nucleobase and having the general Formula (I), (II) and (III) and their tautomeric forms, stereoisomers, pharmaceutically acceptable salts, and their combination with suitable medicament, corresponding processes for the synthesis and pharmaceutical compositions and uses of compounds containing the present invention.