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1. (WO2018197873) MODIFIED COMPLEMENT PROTEINS AND USES THEREOF
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Pub. No.: WO/2018/197873 International Application No.: PCT/GB2018/051087
Publication Date: 01.11.2018 International Filing Date: 25.04.2018
IPC:
C07K 14/47 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
Applicants:
UNIVERSITY OF NEWCASTLE UPON TYNE [GB/GB]; Kings Gate Newcastle Upon Tyne Tyne and Wear NE1 7RU, GB
Inventors:
MARCHBANK, Kevin; GB
YANG, Yi; GB
Agent:
SECERNA LLP; The Catalyst Baird Lane, Heslington East York Yorkshire YO10 5GA, GB
Priority Data:
1706808.128.04.2017GB
1707248.905.05.2017GB
Title (EN) MODIFIED COMPLEMENT PROTEINS AND USES THEREOF
(FR) PROTÉINES DU COMPLÉMENT MODIFIÉES ET UTILISATIONS DE CELLES-CI
Abstract:
(EN) Certain embodiments of the present invention relate to regulation of the innate immune system and complement activation. In particular, but not exclusively certain embodiments relate to a complement regulator protein and pharmaceutical compositions thereof for use in the treatment of diseases associated with or mediated by the alternative complement pathway and methods of treating such diseases and other subject matter.
(FR) Selon certains modes de réalisation, la présente invention concerne la régulation du système immunitaire inné et l'activation du complément. En particulier, mais non exclusivement, certains modes de réalisation de l'invention concernent une protéine régulatrice du complément et des compositions pharmaceutiques de celle-ci destinées à être utilisées dans le traitement de maladies associées à ou induites par la voie alternative du complément ainsi que des procédés de traitement de telles maladies et d'autres objets.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)