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1. (WO2018197859) CANCER TREATMENT

Pub. No.:    WO/2018/197859    International Application No.:    PCT/GB2018/051070
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Wed Apr 25 01:59:59 CEST 2018
IPC: C07K 14/525
C07K 14/54
C12N 15/113
C12N 15/86
C12N 7/00
C12N 7/04
A61K 33/24
A61K 39/00
A61K 48/00
Applicants: IMPERIAL INNOVATIONS LIMITED
Inventors: HAJITOU, Amin
SUWAN, Keittisak
ALBAHRANI, Mariam
WARAMIT, Sajee
Title: CANCER TREATMENT
Abstract:
The present invention provides phagemid vectors and associated phagemid particles for cancer treatment, and in particular, to the use of novel phagemid particles and associated expression systems for the treatment, prevention, amelioration, or management of cancer. In particular, the invention relates to the use of phagemid particles and expression systems for the delivery of transgenes encoding cytokines, for the treatment, prevention, amelioration, or management of cancer. The invention also extends to the use of phagemid particles and expression systems for the delivery of transgenes, and for the combination of such treatment with the use of adoptively transferred T cells, for the treatment, prevention, amelioration, or management of cancer.