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1. (WO2018197416) BIOMIMETIC DOUBLE NETWORK HYDROGELS

Pub. No.:    WO/2018/197416    International Application No.:    PCT/EP2018/060348
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Tue Apr 24 01:59:59 CEST 2018
IPC: C08J 3/075
C08J 3/24
C08L 33/02
C08L 33/26
C09D 133/02
C09D 133/26
Applicants: STICHTING KATHOLIEKE UNIVERSITEIT
Inventors: KOUWER, Paul
ROWAN, Alan
JASPERS, Maarten
DE ALMEIDA, Paula
Title: BIOMIMETIC DOUBLE NETWORK HYDROGELS
Abstract:
The invention relates to a double network hydrogel comprising a polymer (A) having a persistence length between 10 and 1000 nm; a flexible polymer (B), wherein the persistence length is measured according to single molecule force microscopy measurement, wherein polymer (B) has an extended coil conformation at a first condition and a collapsed globular conformation at a second condition. Polymer (A) preferably is a polyisocyanate, while polymer (B) is a crosslinked flexible polymer like for example PNIPAM. The invention also relates to a method for making a double network hydrogel.