Search International and National Patent Collections

1. (WO2018195650) ENHANCED ELECTROPORATION OF CARDIAC TISSUE

Pub. No.:    WO/2018/195650    International Application No.:    PCT/CA2018/050324
Publication Date: Fri Nov 02 00:59:59 CET 2018 International Filing Date: Sat Mar 17 00:59:59 CET 2018
IPC: A61B 18/12
A61B 18/04
A61B 18/14
Applicants: MEDTRONIC CRYOCATH LP
Inventors: STEWART, Mark T.
HOWARD, Brian T.
FRAASCH, Steven J.
Title: ENHANCED ELECTROPORATION OF CARDIAC TISSUE
Abstract:
30 ABSTRACT A device, system, and method for delivering energy to tissue. In particular, the present invention relates to a system and method for enhancing lesion formation without arrhythmogenic effects within relatively thick target tissues, such as the ventricles of the heart. In one embodiment, charge-neutral pulses and non-charge-neutral pulses may be delivered to induce the formation of electrolytic compounds that enhance cell death at the treatment site. Additionally or alternatively, tissue at the treatment site may be heated to sub-lethal temperature before ablating the tissue.