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1. (WO2018193565) METHOD FOR EVALUATING IMPACT OF TEST SUBSTANCE OR PRODUCT ON SKIN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2018/193565 International Application No.: PCT/JP2017/015796
Publication Date: 25.10.2018 International Filing Date: 19.04.2017
IPC:
G01N 33/50 (2006.01) ,G01N 21/65 (2006.01) ,G01N 33/15 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
62
Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63
optically excited
65
Raman scattering
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
15
Medicinal preparations
Applicants:
花王株式会社 KAO CORPORATION [JP/JP]; 東京都中央区日本橋茅場町一丁目14番10号 14-10, Nihonbashi Kayabacho 1-chome, Chuo-ku, Tokyo 1038210, JP
Inventors:
布施 千絵 FUSE, Chie; JP
森崎 尚子 MORISAKI, Naoko; JP
志摩 恭子 SHIMA, Kyoko; JP
市橋 俊希 ICHIHASHI, Toshiki; JP
Agent:
飯田 敏三 IIDA, Toshizo; JP
星野 宏和 HOSHINO, Hirokazu; JP
Priority Data:
Title (EN) METHOD FOR EVALUATING IMPACT OF TEST SUBSTANCE OR PRODUCT ON SKIN
(FR) PROCÉDÉ D’ÉVALUATION DE L’IMPACT D’UNE SUBSTANCE OU D’UN PRODUIT D’ESSAI SUR LA PEAU
(JA) 被験物質又は物品が皮膚に与える影響を評価する方法
Abstract:
(EN) A test substance or product evaluation method which involves contacting human skin with a test substance or product, comparing the amount of change in the skin water content or water distribution before and after contact with a reference value, and on the basis of the comparison results, evaluating the impact which the test substance or product has on the skin barrier function, wherein the skin barrier function is associated with the skin water content or water distribution measured by subjecting the skin to a water loading test by changing the water loading amount, and the skin water content or water distribution when a change in the skin barrier function is confirmed is set as the reference value on the basis of the association between the skin barrier function and the skin water content or water distribution.
(FR) La présente invention concerne un procédé d’évaluation de substance ou de produit d’essai qui met en œuvre la mise en contact de peau humaine avec une substance ou un produit d’essai, la comparaison de la quantité de changement de la teneur en eau ou de la distribution d’eau de la peau avant et après le contact à une valeur de référence et, sur la base des résultats de la comparaison, l’évaluation de l’impact que la substance ou le produit d’essai a sur la fonction de barrière cutanée, la fonction de barrière cutanée étant associée à la teneur en eau ou la distribution d’eau de la peau mesurée en soumettant la peau à un test de chargement d’eau en modifiant la quantité de chargement d’eau, et la teneur en eau ou la distribution d’eau de la peau lorsqu’un changement de la fonction de barrière cutanée est confirmé est définie en tant que valeur de référence sur la base de l’association entre la fonction de barrière cutanée et la teneur en eau ou la distribution d’eau de la peau.
(JA) 被験物質又は物品をヒトの皮膚に接触させ、 接触前後の皮膚の水分量又は水分分布の変化量を、基準値と比較し、 比較結果から、前記被験物質又は物品が、皮膚バリア機能に与える影響を評価する、 被験物質又は物品の評価方法であって、 水の負荷量を変えての皮膚への水負荷試験により測定された、皮膚の水分量又は水分分布と、皮膚のバリア機能とが関連付けられ、 皮膚の水分量又は水分分布と皮膚のバリア機能との関連性から、皮膚のバリア機能に変化が確認されるときの皮膚の水分量又は水分分布が、前記基準値として設定されたものである、 被験物質又は物品の評価方法。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)