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1. (WO2018185781) MICROFACS FOR DETECTION AND ISOLATION OF TARGET CELLS

Pub. No.:    WO/2018/185781    International Application No.:    PCT/IN2018/050194
Publication Date: Fri Oct 12 01:59:59 CEST 2018 International Filing Date: Fri Apr 06 01:59:59 CEST 2018
IPC: G01N 33/00
G01N 21/00
B01L 3/00
Applicants: INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IIT MADRAS)
Inventors: SEN, Ashis Kumar
SRIVASTAVA, Abhishek
GAIKWAD, Ravindra
S, Karthick
K S, Jayaprakash
D, Abhishek Raj
M, Sneha Maria
SHIVHARE, Priyankar
Title: MICROFACS FOR DETECTION AND ISOLATION OF TARGET CELLS
Abstract:
The present invention relates to the detection and isolation of target cells based on microfluidics and cell sorting technology (MicroFACS). In this method the biological cells and microparticles are encapsulated inside hydrodynamically generated droplets and analyzed using suitable optics based on fluorescence and scattering signals. Once the target cells are detected, the optics triggers electro-coalescence for sorting of the target cells into an aqueous stream.