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1. (WO2018185756) MUTANT ALPHA-1-ANTITRYPSIN COMPOSITIONS AND USE THEREOF

Pub. No.:    WO/2018/185756    International Application No.:    PCT/IL2018/050385
Publication Date: Fri Oct 12 01:59:59 CEST 2018 International Filing Date: Tue Apr 03 01:59:59 CEST 2018
IPC: C07K 14/81
C07K 16/18
A61K 38/55
A61K 39/395
Applicants: B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY
Inventors: LEWIS, Eli Chaim
LIOR, Yotam
Title: MUTANT ALPHA-1-ANTITRYPSIN COMPOSITIONS AND USE THEREOF
Abstract:
The present invention provides mutant alpha 1 -antitrypsin proteins, pharmaceutical compositions comprising the same, and methods of use thereof in treatment of subjects with an inflammatory disease or disorder.