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1. (WO2018185468) GENETIC CONSTRUCT FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDER OR STROKE

Pub. No.:    WO/2018/185468    International Application No.:    PCT/GB2018/050824
Publication Date: Fri Oct 12 01:59:59 CEST 2018 International Filing Date: Thu Mar 29 01:59:59 CEST 2018
IPC: A61K 38/17
A61K 38/18
A61P 25/28
A61P 27/06
C12N 15/63
C12N 15/861
Applicants: QUETHERA LIMITED
Inventors: WIDDOWSON, Peter
MARTIN, Keith
Title: GENETIC CONSTRUCT FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDER OR STROKE
Abstract:
The invention provides genetic constructs and recombinant vectors comprising such constructs. The constructs and vectors can be used in gene therapy methods for the treatment, prevention or amelioration of a neurodegenerative disorder, including Alzheimer's disease, Parkinson's disease, Huntington's disease, motor neurone disease, or for the treatment of stroke, or for promoting nerve regeneration and/or survival.