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|1. (WO2018185290) USE OF A LIPOSOME ENCAPSULATING A SUGAR COMPOUND IN CEST IMAGING|
|Applicants:||UCL BUSINESS PLC
|Title:||USE OF A LIPOSOME ENCAPSULATING A SUGAR COMPOUND IN CEST IMAGING|
The invention provides agents for use in methods of saturation transfer mediated imaging (such as CEST imaging) in a subject, which agents comprise a liposome encapsulating a suitable sugar compound. The disclosure provides novel liposome formulations, which can be used for diagnostic and theranostic purposes. The liposomes can be shielded and\or targeted to a sugar uptake site such as a tumour. The invention has particular utility in modulating the glycaemic response to the encapsulated sugar compound in the subject.