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1. (WO2018185266) NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA.

Pub. No.:    WO/2018/185266    International Application No.:    PCT/EP2018/058823
Publication Date: Fri Oct 12 01:59:59 CEST 2018 International Filing Date: Sat Apr 07 01:59:59 CEST 2018
IPC: C07D 417/12
C07D 275/06
C07F 5/02
A61P 35/00
A61K 31/425
Applicants: INVENTIVA
Inventors: BARTH, Martine
CONTAL, Sylvie
Title: NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA.
Abstract:
The invention relates to compounds of formula: wherein R1 to R7 are as defined in the description. These compounds are useful as inhibitors of the YAP/TAZ-TEAD interaction.