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1. (WO2018185210) FURTHER NOVEL OLIGONUCLEOTIDE-LIGAND CONJUGATES

Pub. No.:    WO/2018/185210    International Application No.:    PCT/EP2018/058708
Publication Date: Fri Oct 12 01:59:59 CEST 2018 International Filing Date: Fri Apr 06 01:59:59 CEST 2018
IPC: C07H 21/00
A61K 31/7088
A61P 1/16
A61P 3/06
A61P 9/00
Applicants: SILENCE THERAPEUTICS GMBH
Inventors: SAMARSKY, Dmitry
FRAUENDORF, Christian
Title: FURTHER NOVEL OLIGONUCLEOTIDE-LIGAND CONJUGATES
Abstract:
The present invention relates to a compound comprising a modified saccharide moiety conjugated to a nucleic acid. The compound is useful in medicine for RNA interference therapy or for research and diagnostic purposes. In particular, the compound is useful in treating liver disease.