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1. (WO2018184966) ANTIBODIES BINDING TO STEAP-1

Pub. No.:    WO/2018/184966    International Application No.:    PCT/EP2018/058043
Publication Date: Fri Oct 12 01:59:59 CEST 2018 International Filing Date: Fri Mar 30 01:59:59 CEST 2018
IPC: C07K 16/30
A61K 47/68
A61K 39/00
Applicants: F. HOFFMANN-LA ROCHE AG
HOFFMANN-LA ROCHE INC.
Inventors: HOFER, Thomas
KOENIG, Maximiliane
MOESSNER, Ekkehard
NIEWOEHNER, Jens
WEINZIERL, Tina
LARIVIERE, Laurent
Title: ANTIBODIES BINDING TO STEAP-1
Abstract:
The present invention generally relates to antibodies that bind to STEAP-1, including bispecific antigen binding molecules e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.