Search International and National Patent Collections

1. (WO2018184933) RACEMIC BETA-AMINOSULFONE COMPOUNDS

Pub. No.:    WO/2018/184933    International Application No.:    PCT/EP2018/057894
Publication Date: Fri Oct 12 01:59:59 CEST 2018 International Filing Date: Thu Mar 29 01:59:59 CEST 2018
IPC: C07C 317/28
C07C 251/28
Applicants: QUIMICA SINTETICA, S. A.
Inventors: BARRECA, Giuseppe
MARRAS, Giovanni
MORANA, Fabio
Title: RACEMIC BETA-AMINOSULFONE COMPOUNDS
Abstract:
It is described an industrially viable and advantageous process for the preparation of racemic beta-aminosulfone (1), an useful intermediate for the preparation of N-(2-((1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl)acetamide, also known as Apremilast, the latter being suitable for use in methods of treating, preventing and/or managing psoriasis or psoriatic arthritis.