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1. (WO2018184196) METHOD FOR PREPARING 2-ARYLMALONAMIDE AND APPLICATIONS OF METHOD

Pub. No.:    WO/2018/184196    International Application No.:    PCT/CN2017/079686
Publication Date: Fri Oct 12 01:59:59 CEST 2018 International Filing Date: Sat Apr 08 01:59:59 CEST 2017
IPC: C07D 498/04
C07C 233/11
Applicants: ORIENTAL(LUZHOU) AGROCHEMICALS. CO., LTD.
泸州东方农化有限公司
Inventors: SUN, Yinwei
孙殷卫
WANG, Zhongyuan
王忠元
HUANG, Yanyan
黄艳艳
CHEN, Bangchi
陈邦池
Title: METHOD FOR PREPARING 2-ARYLMALONAMIDE AND APPLICATIONS OF METHOD
Abstract:
Provided are a method for preparing 2-arylmalonamide and applications of the method. The method uses 2-(cyclohexylene) malononitrile as raw material that undergoes an aromatization-hydrolysis reaction under the effects of an oxidizer and water to produce in one step 2-arylmalonamide. Compared with the prior art, the method provided in the present invention for preparing 2-arylmalonamide has the following significant characteristics and advantages: (1) a completely different synthesis strategy; (2) the raw material is simple and easy to obtain; (3) a high yield, and at the same time, with the use of an expensive metal catalyst avoided, inexpensiveness and suitability for industrial production.