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1. (WO2018183986) GUT-SELECTIVE SEQUESTERING AGENTS FOR THE TREATMENT AND PREVENTION OF AUTISM AND RELATED DISORDERS
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Pub. No.: WO/2018/183986 International Application No.: PCT/US2018/025607
Publication Date: 04.10.2018 International Filing Date: 31.03.2018
IPC:
A61K 33/44 (2006.01) ,A23L 33/29 (2016.01) ,A61P 25/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
44
Elemental carbon, e.g. charcoal, carbon black
[IPC code unknown for A23L 33/29]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
Applicants:
AXIAL BIOTHERAPEUTICS, INC. [US/US]; 745 Boylston Street 6th Floor, Suite 602 Boston, MA 02116, US
Inventors:
CAMPBELL, Anthony, Stewart; US
DONABEDIAN, David, H.; US
Agent:
TWOMEY, Michael, J.; US
Priority Data:
62/480,03931.03.2017US
Title (EN) GUT-SELECTIVE SEQUESTERING AGENTS FOR THE TREATMENT AND PREVENTION OF AUTISM AND RELATED DISORDERS
(FR) AGENTS DE SÉQUESTRATION SÉLECTIFS DE L’INTESTIN POUR LE TRAITEMENT ET LA PRÉVENTION DE L’AUTISME ET DE TROUBLES ASSOCIÉS
Abstract:
(EN) The present disclosure describes methods and compositions for the treatment of neurological disorders and related symptoms by the in vivo sequestration and excretion of microbial metabolites. These metabolites are related to neurological disorders such as autism and Parkinson's disease, as well as intestinal hyperpermeability (leaky gut) and gastrointestinal comorbidities associated with such disorders.
(FR) La présente invention concerne des procédés et des compositions pour le traitement de troubles neurologiques et de symptômes associés par la séquestration et l’excrétion in vivo de métabolites microbiens. Ces métabolites sont associés à des troubles neurologiques tels que l’autisme et la maladie de Parkinson, ainsi que l’hyperperméabilité intestinale (fuite intestinale) et les comorbidités gastro-intestinales associées à de tels troubles.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)