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1. (WO2018183868) INHIBITORS OF DNA PK AND USES THEREOF
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Pub. No.: WO/2018/183868 International Application No.: PCT/US2018/025430
Publication Date: 04.10.2018 International Filing Date: 30.03.2018
IPC:
A61K 31/06 (2006.01) ,A61P 37/06 (2006.01) ,C07D 221/00 (2006.01)
[IPC code unknown for A61K 31/06][IPC code unknown for A61P 37/06][IPC code unknown for C07D 221]
Applicants:
BIOVENTURES, LLC [US/US]; 4301 W. Markham St., #831 Little Rock, Arkansas 72205-7199, US
ARKANSAS CHILDREN'S RESEARCH INSTITUTE [US/US]; 13 Children's Way, Slot #842 Little Rock, Arkansas 72202, US
Inventors:
BURDINE, Lyle; US
BURDINE, Marie; US
KIM WIESE, Ara; US
Agent:
JOHNSON, Charles A.; US
DOTY, Kathryn; US
RILEY-VARGAS, Rebecca; US
ROBERTS, Brett J.; US
BISSEN, Shirley T.; US
NEALEY, Tara A.; US
KREPEL, Allison; US
Priority Data:
62/479,94531.03.2017US
Title (EN) INHIBITORS OF DNA PK AND USES THEREOF
(FR) INHIBITEURS DE PROTÉINE KINASE DÉPENDANTE DE L'ADN (DNA-PK) ET LEURS UTILISATIONS
Abstract:
(EN) The present disclosure relates to compositions and methods for improving the transplantation outcome and/or reducing immune response in a subject. The compositions comprise a DNA-PK inhibitor.
(FR) La présente invention concerne des compositions et des procédés permettant d'améliorer le résultat d'une transplantation et/ou de réduire la réponse immunitaire chez un sujet. Lesdites compositions comprennent un inhibiteur de protéine kinase dépendante de l'ADN (DNA-PK).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)