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1. (WO2018183668) QUINOLINE DERIVED SMALL MOLECULE INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF

Pub. No.:    WO/2018/183668    International Application No.:    PCT/US2018/025134
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Fri Mar 30 01:59:59 CEST 2018
IPC: A61K 31/47
A61K 31/4709
A61K 31/5377
Applicants: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Inventors: WATOWICH, Stanley
NEELAKANTAN, Harshini
MCHARDY, Stanton
WANG, Hua-Yu
Title: QUINOLINE DERIVED SMALL MOLECULE INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF
Abstract:
The present invention relates to quinoline derived small molecule inhibitors of nicotinamide N-methyltransferase (NNMT), the preparation thereof and uses thereof. Formula (I).