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1. (WO2018183608) COMBINATION THERAPY FOR CANCER USING ANTI-GITR ANTIBODIES

Pub. No.:    WO/2018/183608    International Application No.:    PCT/US2018/025034
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Fri Mar 30 01:59:59 CEST 2018
IPC: C07K 16/28
A61K 39/395
A61P 35/00
A61K 39/00
Applicants: FIVE PRIME THERAPEUTICS, INC.
Inventors: BARBEE, Susannah D.
BELLOVIN, David
BORGES, Luis
Title: COMBINATION THERAPY FOR CANCER USING ANTI-GITR ANTIBODIES
Abstract:
Provided herein are methods of treating cancer with a combination of an anti glucocorticoid-induced tumor necrosis factor receptor (TNFR)-related protein (GITR)-antibody and an antibody that binds colony stimulating factor 1 receptor (CSF1R) or with a combination of an anti-GITR antibody and an antibody that binds programmed cell death protein 1 (PD-1).