A separation system includes a column including a stripping section proximal to a lower end of the column, a rectifying section proximal to an upper end of the column, and an intermediate section disposed between the stripping section and the rectifying section. The intermediate section includes first and second vertical sides separated by a vertical wall. The column includes a feed port to receive a material stream to be separated. The separation system further includes a reboiler in fluid communication with the column. The reboiler provides vapor to the stripping section. The separation system also includes a condenser in fluid communication with the column. The condenser provides liquid to the rectifying section, the condenser to provide a distillate effluent stream. The separation system further includes an active vapor control to control the relative vapor flow rate to the first and second sections.