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1. (WO2018183203) PACKAGED MULTI-DOSE LIQUID DRUG FORMULATION
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Pub. No.: WO/2018/183203 International Application No.: PCT/US2018/024366
Publication Date: 04.10.2018 International Filing Date: 26.03.2018
IPC:
A61K 31/485 (2006.01) ,A61K 9/08 (2006.01) ,A61K 47/10 (2017.01) ,A61P 11/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
485
Morphinan derivatives, e.g. morphine, codeine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
08
Solutions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
14
Antitussive agents
Applicants:
DXM PHARMACEUTICAL, INC. [US/US]; 2717 Commercial Center Boulevard Suite E200 Katy, TX 77494, US
Inventors:
THUESEN, Mark, Lawrence; US
SANDERS, Steve, Shane; US
BANNISTER, Steve, J.; US
Agent:
WILLHELM, Keith B.; US
Priority Data:
15/932,03026.01.2018US
15/936,12926.03.2018US
62/476,92127.03.2017US
Title (EN) PACKAGED MULTI-DOSE LIQUID DRUG FORMULATION
(FR) FORMULATION DE MÉDICAMENT LIQUIDE À DOSES MULTIPLES CONDITIONNÉE
Abstract:
(EN) Multi-dose packaged over-the-counter antitussive syrups comprise a bottle containing about 75 ml or less of a liquid formulation of dextromethorphan hydrobromide. The liquid formulation provides at least two doses of dextromethorphan hydrobromide. Multi-dose packaged over-the-counter liquid formulations comprise a bottle having a capacity of about 100 ml or less, at least two doses of the liquid formulation carried within the bottle, a cap, a dosage cup releasably carried on the cap and a shrink wrap substantially enveloping the bottle and the dosage cup. Antitussive syrups comprise water, dextromethorphan hydrobromide in amounts from about 6 to about 25 mg/ml, and sweetener in amounts from about 200 to about 800 mg/ml.
(FR) Les sirops antitussifs en vente libre conditionnés à doses multiples comprennent une bouteille contenant environ 75 ml ou moins d'une formulation liquide de bromhydrate de dextrométhorphane. La formulation liquide fournit au moins deux doses de bromhydrate de dextrométhorphane. Les formulations liquides en vente libre conditionnés à doses multiples comprennent une bouteille ayant une capacité d'environ 100 ml ou moins, au moins deux doses de la formulation liquide transportées à l'intérieur de la bouteille, un capuchon, une coupelle de dosage portée de façon amovible sur le capuchon et un emballage rétractable enveloppant sensiblement la bouteille et la coupelle de dosage. Les sirops antitussifs comprennent de l'eau, du bromhydrate de dextrométhorphane en des quantités d'environ 6 à environ 25 mg/ml, et un édulcorant dans des quantités d'environ 200 à environ 800 mg/ml.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)