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1. (WO2018183198) PROCESS FOR MAKING ARYLOMYIN RING ANALOGS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/183198 International Application No.: PCT/US2018/024351
Publication Date: 04.10.2018 International Filing Date: 26.03.2018
IPC:
C07D 245/02 (2006.01) ,A61K 31/395 (2006.01) ,A61P 31/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
245
Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
02
not condensed with other rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
Applicants: GENENTECH, INC.[US/US]; 1 DNA Way South San Francisco, California 94080, US (US)
F. HOFFMANN-LA ROCHE AG[CH/CH]; Grenzacherstrasse 124 4070 BASEL, CH (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JO, JP, KE, KG, KH, KM, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW)
Inventors: PETRONIJEVIC, Filip; US
LIM, Ngiap-Kie; US
WONG, Nicholas; US
HONG, Allen; US
HOU, Haiyun; US
LINGHU, Xin; US
GOSSELIN, Francis; US
Agent: HALL, Robert C.; US
ACKERMAN, Lily J.; US
AUSENHUS, Scott L.; US
BERENDT, Frank JN; US
BUCKWALTER, Brian L.; US
CHANG, Y. Elaine; US
CHI, I. Shannon; US
CLARK, Kevin M.; US
COBURN, Cara M.; US
COLANTINO, Jessica R.; US
CRISSEY, Todd M.; US
CUI, Steven; US
DAVIS, Jennifer L.; US
DUFFIELD, Jonathan J.; US
FANG, Carol A.; US
GHOSE, Shameek; US
HEIDER, Julie A.; US
HILL, Laurie L.; US
HOLMES, Jennifer K.; US
JOHNSTON, Sean A.; US
KAFKA, Mark D.; US
KALE, Tamara A.; US
KALINOWSKI, Grant E.; US
KUBINEC, Jeffrey S.; US
LEE, Wendy M.; US
LI, Qianru; US
MARSCHANG, Diane L.; US
MCCLELLAN, Kelly B.; US
PAZDERA, R. Minako; US
RICHARDSON, Jessica L.; US
ROPP, Traci H.; US
SCHWARTZ, Timothy R.; US
SHERMAN, Daniel E.; US
SHIN, Elinor K.; US
TAN, Anna M.; US
TIAN, Zong-Qiang Bill; US
WAIS, Rebecca J.; US
YEUNG, Bonny G.; US
DREGER, Ginger; US
Priority Data:
62/477,26827.03.2017US
Title (EN) PROCESS FOR MAKING ARYLOMYIN RING ANALOGS
(FR) PROCÉDÉ DE FABRICATION D'ANALOGUES DE L'ANNEAU D'ARYLOMYCINE
Abstract:
(EN) Methods for making an arylomycin ring of formula t or salts or solvates thereof, wherein R, R1, R2, R3, R4, R5, R6, R7, R8, R9, R5, R10 and Pg1 are as defined herein.
(FR) L'invention concerne des procédés de fabrication d'un anneau d'arylomycine de formule t ou des sels ou solvates de celui-ci. Dans la formule R1, R2, R3, R4, R5, R6, R7, R8, R9, R5, R10 et Pg1 sont tels que définis dans la description.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)