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1. (WO2018183182) METHODS AND COMPOSITIONS FOR REDUCTION OF IMMUNOGENICITY
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2018/183182 International Application No.: PCT/US2018/024316
Publication Date: 04.10.2018 International Filing Date: 26.03.2018
IPC:
C07K 16/28 (2006.01) ,A61K 39/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants:
CELGENE CORPORATION [US/US]; 86 Morris Avenue Summit, NJ 07901, US
Inventors:
JOHNSON, Jeffrey, C.; US
DEARTH, Lawrence; US
HADJIVASSILIOU, Haralambos; US
SUN, Jeonghoon; US
HARIHARAN, Kandasamy; US
Agent:
GEORGE, Nikolaos, C.; US
BHUMRALKAR, Megha; US
BRUNER, Michael, J.; US
RIEGER, Dale, L.; US
INSOGNA, Anthony, M.; US
Priority Data:
62/477,25727.03.2017US
Title (EN) METHODS AND COMPOSITIONS FOR REDUCTION OF IMMUNOGENICITY
(FR) PROCÉDÉS ET COMPOSITIONS POUR LA RÉDUCTION D'IMMUNOGÉNICITÉ
Abstract:
(EN) Provided herein are methods and uses involving the combination of an anti-CD20 antibody, e.g., rituximab with a protein therapeutic, for example, an antibody (e.g., an antibody that specifically binds to human CD47).
(FR) La présente invention concerne des procédés et des utilisations impliquant la combinaison d'un anticorps anti-CD20, par exemple le rituximab avec une protéine thérapeutique, par exemple, un anticorps (par exemple, un anticorps qui se lie de manière spécifique à CD47 humain).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)