Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018182983) NOROVIRUS S PARTICLE BASED VACCINES AND METHODS OF MAKING AND USING SAME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/182983 International Application No.: PCT/US2018/022552
Publication Date: 04.10.2018 International Filing Date: 15.03.2018
IPC:
A61K 39/00 (2006.01) ,A61K 39/12 (2006.01) ,A61K 39/125 (2006.01) ,A61K 39/295 (2006.01) ,A61P 31/14 (2006.01) ,C07K 14/005 (2006.01)
[IPC code unknown for A61K 39][IPC code unknown for A61K 39/12][IPC code unknown for A61K 39/125][IPC code unknown for A61K 39/295][IPC code unknown for A61P 31/14][IPC code unknown for C07K 14/05]
Applicants:
CHILDREN'S HOSPITAL MEDICAL CENTER [US/US]; 3333 Burnett Avenue Cincinnati, OH 45229, US
Inventors:
TAN, Ming; US
JIANG, Xi, Jason; US
Agent:
TEPE, Nicole, M.; US
GOLDSTEIN, Steven, J.; US
SCHOEN, Ann, G.; US
ACHESON, Edwin, R.; US
CONLEY, Scott, R.; US
Priority Data:
62/477,48128.03.2017US
Title (EN) NOROVIRUS S PARTICLE BASED VACCINES AND METHODS OF MAKING AND USING SAME
(FR) VACCINS À BASE DE PARTICULES S DE NOROVIRUS ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
Abstract:
(EN) Disclosed herein are vaccine compositions, in particular, polyvalent icosahedral compositions for antigen presentation. The disclosed compositions may contain an S particle made up of recombinant fusion proteins. The recombinant fusion proteins may include a norovirus (NoV) S domain protein, a linker protein domain operatively connected to the norovirus S domain protein, and an antigen protein domain operatively connected to said linker.
(FR) La présente invention concerne des préparations vaccinales, en particulier, des préparations icosaédriques polyvalentes de présentation à l'antigène. Les préparations divulguées peuvent contenir une particule S constituée de protéines de fusion recombinantes. Les protéines de fusion recombinantes peuvent comprendre une protéine de domaine S de norovirus(NoV), un domaine de protéine lieur lié fonctionnellement à la protéine de domaine S de norovirus et un domaine de protéine d'antigène fonctionnellement relié audit lieur.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)