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1. (WO2018182776) FOLATE CONJUGATE FOR USE IN TARGETING TUMOR ASSOCIATED MACROPHAGES

Pub. No.:    WO/2018/182776    International Application No.:    PCT/US2017/051662
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Fri Sep 15 01:59:59 CEST 2017
IPC: A61K 45/06
A61P 35/00
Applicants: ENDOCYTE, INC.
Inventors: VLAHOV, Iontcho Radoslavov
LEAMON, Christopher Paul
QI, Longwu
ZOU, Ning
WANG, Kevin Yu
FELTEN, Albert E.
PARHAM, Garth L.
YOU, Fei
SANTHAPURAM, Hari Krishna R.
HAHN, Spencer J.
REDDY, Joseph Anand
LU, Yingjuan J.
WHEELER, II, Leroy W.
Title: FOLATE CONJUGATE FOR USE IN TARGETING TUMOR ASSOCIATED MACROPHAGES
Abstract:
Methods are provided for treating cancers using a conjugate herein described as Conjugate 5, or a pharmaceutically acceptable salt thereof. Methods for treating cancers using Conjugate 5, or a pharmaceutically acceptable salt thereof, to target tumor associated macrophages are also described.